Molecules, Free Full-Text
Por um escritor misterioso
Descrição
Extracellular vesicles (EVs), including exosomes, have an important role thanks to their ability to communicate and exchange information between tumor cells and the tumor microenvironment (TME), and have also been associated with communicating anti-cancer drug resistance (DR). The increase in proliferation of cancer cells alters oxygen levels, which causes hypoxia and results in a release of exosomes by the cancer cells. In this review, the results of studies examining the role of exosomal miRNA in DR, and their mechanism, are discussed in detail in hematological tumors: leukemia, lymphoma, and multiple myeloma. In conclusion, we underline the exosome’s function as a possible drug delivery vehicle by understanding its cargo. Engineered exosomes can be used to be more specific for personalized therapy.
A sketch of the simulation model. Prompt X‐rays incident from the left
Clinical and Translational Medicine - Wiley Online Library
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Molecules Set of 4 Art PRINTABLES Caffeine Happiness Sleep
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules.
Molecules, Free Full-Text
Molecules An Open Access Journal from MDPI
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